Hierarchical dynamics in allostery following ATP hydrolysis monitored by single molecule FRET measurements and MD simulations

نویسندگان

چکیده

We report on a study that combines advanced fluorescence methods with molecular dynamics simulations to cover timescales from nanoseconds milliseconds for large protein, the chaperone Hsp90.

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ژورنال

عنوان ژورنال: Chemical Science

سال: 2021

ISSN: ['2041-6520', '2041-6539']

DOI: https://doi.org/10.1039/d0sc06134d